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ProHance Side Effects Lawsuit

ProHance Side Effects Lawsuit

ProHance, brand name of Gadoteridol, is a popular gadolinium-based contrast agent manufactured by pharmaceuticals major Bracco Diagnostic. The contrast drug helps in improved MRI of the central nervous system. ProHance also helps radiologists easily distinguish leaky blood vessels and problematic tissues in patients during MRI scans. However, the side effects of the drug can lead to rare disorders, such as Nephrogenic Systemic Fibrosis and Nephrogenic Fibrosing Dermopathy, in people with impaired renal function. It has also been linked to liver problems, cardiovascular side effects, skin diseases, and other potentially life-threatening conditions.

ProHance and FDA Warnings

The FDA approved ProHance in 1999 for clinical use. Following numerous reports of epidermal and dermal side effects, the FDA issued a public health advisory in June 2006, informing health professionals about possible fatal skin disorders caused by the drug. A study by the Danish Health Authority in 2007 highlighted 25 Nephrogenic Systemic Fibrosis cases, where patients with impaired kidney and liver functions developed the rare disorder after taking gadolinium-based contrast injections during diagnostic tests.

The findings of the Danish report prompted the FDA to

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Turkey Recall Lawsuit

Cargill Meat Recalls Turkey Meat
Cargill Meat Solutions has recalled 36 million pounds of ground turkey meat potentially contaminated by salmonella bacteria. The second biggest U.S. meat recall was prompted after a nationwide salmonella outbreak resulted in the death of one consumer in California and hospitalization of 76 others in 26 states. The illness caused by salmonella outbreak was first reported on March 7th. It spread from coast to coast by mid-July. The Food Safety and Inspection Service of the U.S. Department of Agriculture issued a public health alert on July 29th confirming the link between the illness caused by the bacteria and the ground turkey meat. It ordered for the investigation after some leftovers from turkey meat recovered from a victim’s house were found infected with salmonella bacteria.
The USDA informed the Cargill management of its findings on August 3rd that triggered the recall. According to a press release, the Minnesota-based company is recalling all fresh and frozen turkey products processed at its plant in Springdale, Arkansas, between February 20th and August 2nd 2011 for possible infection from the strain of salmonella. The affected packages bear the code "Est. P-963" and are sold under different meat and grocery store brands, such as Honeysuckle White, HEB, Riverside Ground Turkey, Safeway, Natural Lean Ground Turkey, Kroger, Fit & Active Lean Ground Turkey, Randall's, Tom Thumb Spartan Ground Turkey, Giant Eagle, and Shady Brook Farms Burgers.
Salmonella Health Hazards
According to the Center for Disease Control and Prevention, the ground turkey products are contaminated with Salmonella Heidelberg bacteria that can resist multiple drugs, including antibiotics. It can cause infection, resulting in diarrhea, abdominal cramps, and acute fever within 12 hours of entering the intestine. Though the sickness lasts for a week, it can cause fatal health problems when the bacteria spread to bloodstream and other vital organs in the body. Severe salmonella infection can cause death of infants, seniors, and those with impaired immune systems. The infection caused by the bacteria has also been linked to a type of rare kidney failure, known as hemolytic uremic syndrome.
Previous Recalls by Cargill
Cargill and its subsidiaries have made 10 recalls since 1993. The present recall is
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Provera Side Effects Lawsuit



Provera Side Effects Lawsuits

Provera Side Effects LawsuitProvera, manufactured by Upjohn Pharmaceuticals, a unit of Pfizer, has been linked to breast and uterine cancer, blood clot disorder, and a number of other side effects. The drug made up of medroxyprogesterone acetate is used to treat menopausal symptoms, abnormal menstrual cycle changes in females, irregular menstrual, uterine bleeding, and premenstrual tension. It regulates secretion of progesterone, a female sex hormone regulating ovulation and menstrual periods. The drug also prevents overgrowth of the uterine lining caused by estrogen replacement therapy.

Provera Side Effects Warnings

A major study the National Institute of Health conducted in 2002 linked Provera and similar hormone drugs to a significant increase in the risk of cardiovascular problems, blood clots, and breast cancer. The study advised patients having epilepsy, migraines, seizures, asthma, heart problems, and diabetes to avoid the medication or consult the doctor.  According to another research by Women's Health Initiative Memory Study, elderly postmenopausal women treated simultaneously with the drug and the estrogen therapy are more likely to develop dementia.

The FDA has categorized Provera under the pregnancy category D. The drug can cause minor birth defects in children if expectant mothers are administered the drug. There have been reports linking the drug to genital abnormalities in babies born from mothers who took the drug during the first trimester of pregnancy. Male babies born from such mothers are likely to suffer from hypospadias, a condition in which the penis opens underside than the tip. Clitoris enlargement and labia fusion are the foremost problems the female fetus is likely to have due to the drug side effects.

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Zimmer Durom Hip Replacement Implant Lawsuit


Zimmer Durom Hip Replacement Implant

In 2008, Zimmer Holdings suspended sale of Durom Acetabular Cup following numerous complaints of a high implant failure rate. Since 2006, when Durom Cup came to be used in the United States, numerous complaints and lawsuits have been filed against Zimemr Holdings. Most of the lawsuits filed against Zimmer allege that the defendant did not disclose the risks associated with the hip implant cup when it marketed the product. However, Zimmer continues to deny the allegations, precisely blaming the surgeons for the high hip implant failure rate. Many patients have complained that the Durom Cup failed within two years of implantation, as a result of which, they had to bear severe pain and undergo a revision surgery.

Patients complain of pain and stiffness following their hip replacement surgery with Durom Cup. They allege that they experience so much stiffness and sharp pain in the groin that they cannot walk properly. Most of the patients also allege that they even find it difficult to come down the stairs.

Zimmer Durom Cup Dangers

The Durom Cup had been implanted in more than 12,000 patients in the country from 2006 to 2008. According to reports, about 11 percent of the Durom Cup implants failed in the first two years. However, Zimmer claims that the product can last for 15 years, saying that the metal hip replacement system is far more durable than traditional implants.

In fact, the Durom Cup is a metal-on-metal hip replacement system, with multiple metal components designed to fit into a “ball and socket” formation. As the ball rotates and rubs against the cup-like socket, it sometimes presses against the edge of the cup, thus generating a large volume of microscopic metal shavings into the patient’s bloodstream. The metallic debris can be absorbed by the soft tissue, resulting in

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DePuy Hip Replacement Recall Lawsuit


DePuy Pinnacle Hip Replacement Implant Ultamet Recall

Depuy Hip Replacement LawsuitFollowing the DePuy ASR recall, there have been numerous complaints that DePuy Pinnacle hip implant is causing similar problems when used with a metal liner. Patients and doctors demand that, with more than 1,300 adverse event reports filed with the FDA against Pinnacle hip implant, it is high time DePuy Orthopedics issued a recall for the device, which is reported to have a 13 percent failure rate. The device is linked to potential side effects, including severe pain, hip dislocation, hip replacement failure, metal toxicity, and need for a revision surgery in many cases.

The FDA approved the DePuy Pinnacle® Ultamet® metal acetabular inserts in 2001. However, not all Pinnacle hip devices are metal on metal, but the metal bearing surface poses the risk of revision compared to other bearing surfaces, including plastic, polyethylene, ceramic, and polymer. The Pinnacle metal on metal hip replacement system with a femoral head, particularly the one that is more than 32 mm, poses a threat of revision surgery. Though the Pinnacle Ultamet does not have as high a failure rate as ASR implants, a large number of incidences of

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