Alli Side Effects Lawsuit Attorney
Xenical Side Effects Lawsuit Attorney
Roche's Diet Drug Tied to Kidney Damage
The Canadian researchers have reported that Roche's Xenical diet drug enhances the possibility of kidney damage. A survey of the Ontario Province healthcare database revels that 0.5 percent among the new users of orlistat, the active ingredient in Xenical by Swiss pharma major Roche, sought medication for acute kidney problems within a year of starting the drug. The statistics jumped to two percent over the next year. The study report published in the Archives of Internal Medicine took into account 953 samples.
Dr. Matthew Weir, who was the part of the research team, disclosed that there were earlier reports of such cases of kidney problems in patients using Xenical, but it was not mentioned among the side effects of the drug. In 2010, the US Federal Drug Administration issued an advisory underlining the potential cases of liver damages for patients using Roche’s Xenical or GlaxoSmithKline's Alli. The active ingredient in these drugs, orlistat, helps in the fat absorption in the gut. Excessive absorption of oxalate and its subsequent deposition may create complications in the renal parenchyma, liver, and kidney.
Xenical is one of the most used diet drugs in the world. In 2009, it hit $345 million in sales compared to Alli's $317 million global sales. However, none of the diet drug manufacturers have ever commented on side effects that can damage liver and kidney. Dr. Donald E. Greydanus, a noted pediatrician and expert on obesity treatments at Michigan State University, has called on the people using weight loss drugs, such as Xenical, to carefully monitor their kidney functions. According to him, it is essential that people use the so-called weight loss drugs only under the prescription of trusted physicians as all such drugs have variable side effects.
2010 FDA Lever Injury Warning Over Xenical, Alli
In May 2010, the FDA directed pharma giants GlaxoSmithKline and Roche to add new warning about potential liver injury on weight-loss drugs manufactured by them. The drug regulator felt it would be safer to alert users about possible liver damage. It also directed users to consult doctors for symptoms, such as dark urine, itching, yellow eyes or skin, and loss of appetite. The regulator cited 12 cases of severe liver damage abroad caused by Xenical and one in the country due to use of Alli. The data also cited two deaths and three liver transplants necessitated by the side effects of these diet drugs.
DA Recall of Fen Phen Lawsuit Attorney
The recall of Fen Phen is one of the most widely known in the US pharmaceutical industry. The FDA issued a notification in September of 1997 for withdrawal of commonly used diet drug Fen Phen, after the reports confirmed the drug was responsible for primary pulmonary hypertension and valvular disease in patients. Fred Wilson, an official with manufacturer Wyeth, was the first person to bring it to the public notice that the manufacturer had labeled only four out of 41 cases of pulmonary hypertension noticed in the users during the trial. The FDA allowed it controversially though the European regulators demanded a major pulmonary hypertension risk warning on the label.
In 1996, the New England Journal of Medicine reported that fenfluramine, an ingredient in Fen Phen, causes 23-fold increase in pulmonary hypertension. A year later, the Boston herald reported death of a 30-year-old woman because of heart problems which was noticed within a month of using the drug. The FDA put the drug on its MedWatch program after the Mayo Clinic reported 24 cases of heart valve disease associated with Fen Phen. Doctors discovered 30 percent of patients using Fen Phen showed abnormal results. Patients with abnormal echocardiograms were found to become asymptomatic after using it.
The withdrawal request was issued after 75 reports of this drug-induced valvular disease in women involving the aortic and mitral valves were reported. The recall also included Pondimin and Redux for having fenfluramine and dexfenfluramine as ingredients. The American Home Products Corporation, commonly known as Wyeth, offered $4 billion in settlement to all patients who suffered because of using Fen Phen. About six million people were victims of the drug and more than 70,000 lawsuits were filed claiming compensation ranging from prescription refunds to those who suffered heart damage.
Hydroxycut Recall Lawsuit Attorney
On May 1st, 2009, the US health officials warned people asking to stop using the Canadian-made supplement Hydroxycut with immediate effect. The drug was found to have caused serious liver damage in patients. The FDA also cited death of a 19-year-old boy using the drug in 2007. After FDA warning, manufacturer MuscleTech Research and Development, Inc. and distributer Iovate Health Sciences pulled out 14 Hydroxycut products from the market.
The FDA's food and nutrition division found 23 cases of serious liver problems. Most patients had jaundice and liver failure. One of the patients had to undergo liver transplant. The product was branded as a dietary supplement and used to shed pounds and to sharpen muscles. However, its potentially toxic ingredients, including hydroxycitric acid, could potentially damage the liver. The FDA also acknowledged that many cases caused by its side effects remained unreported.
Four years before its recall, a lawsuit was filed by a Missouri attorney on March 27, 2003, challenging the claim of the Hydroxycut's manufacturer that the supplement was clinically proven as a fat-burner. He also claimed that the company had failed to advertise the adverse health risks associated with the dietary supplement. MuscleTech made an out-of-court settlement by paying the plaintiff $100,000 while denying any wrongdoing.
LipoKinetix Diet Drug Recall Lawsuit Attorney
In November 2004, the FDA issued a warning asking consumers to stop use of Lipokinetix, a dietary weight loss supplement by Syntrax Innovations, Inc. The warning was prompted by reports liver injury caused by the drug. The product was also linked to nausea, fatigue, flu-like symptoms, abdominal pain, and skin color changes.
Abbott Recall of Meridia for Causing Heart Problems
The Abbott Laboratories recalled popular diet drug Meridia in the US and Canada in October 2010 after the FDA warned that the product put users at the increased risk for heart attack and stroke. sibutramine, an ingredient in the drug was found responsible for insomnia and rising blood pressure that ultimately resulted in strokes. Sold under names, such as Sibutamine, Reductil, and Reduxade, the drug inhibits natural chemicals in the brain to control appetite, which may lead to sleep disorders. Abdominal pain, constipation, nausea, and kidney problems are also attributed to it. The FDA also forced recall of Slim-30 Herb Supplement by J & H Besta Corp for having the same ingredient.