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Magnevist Side Effects Lawsuit Attorney

 

Magnevist Side Effects Lawsuit Attorney

Bayer’s Magnevist was the first intravenous contrast drug to be approved for clinical use in the United States in 1988. The drug helps make diagnostic tests, such as MRI scans, easier to read. It is administered to patients before they take diagnostic tests to ensure a clear view of leaky blood vessels, organs, and various non-bony tissues in the body. However, patients taking the drug have suffered from several disabling and potentially life-threatening conditions, including liver problems, fatal skin diseases, and Nephrogenic Systemic Fibrosis (NSF) – a rare kidney disease.

 

FDA Warning on Magnevist Side Effects

In June 2006, the FDA first alerted medical practitioners about fatal Magnevist side effects following the identification of 25 Nephrogenic Systemic Fibrosis cases by the Danish Health Authority. A public health advisory by the federal regulator warned about the risk of fatal skin diseases and NFS disorder in kidney and liver patients using gadolinium-based imaging agents, including Magnevist. The drug triggers thickening of the skin, tissues, and organs, causing difficulty in movement and broken bones. In May 2007, the FDA asked the drug manufacturer to add mandatory "Black Box" labels on the drug, alerting patients with kidney and liver problems about possible side effects.

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 Most Reported Drug Side Effects

 

Drug Adverse Reaction Injuries Side Effects Drugs Most Reported for Side Effects

About 2 to 4 million US residents suffered from severe, debilitating, and fatal injuries caused by prescription drug side effects in 2011, according to the Institute for Safe Medication Practices, which monitors drug adverse events in the United States. The annual data published by its QuarterWatch surveillance program shows that the FDA got 179,855 serious drug side effect injury reports in 2011, which include 21,002 reports directly from healthcare professionals and consumers through the MedWatch system and 158,853 adverse events corroborated by manufacturers. The numbers released are 9.4 percent or 15,386 instances more than annual drug injury cases reported in the previous year.

 

Top 10 Drugs Reported for Side Effect Injuries

The Institute for Safe Medication Practices has identified 10 drugs that led the list of adverse events associated with prescription medication in 2011. Anticoagulant medication Pradaxa, produced by German drug maker Boehringer Ingelheim, tops the list, followed by warfarin-based anticoagulant Coumadin - manufactured and marketed by Bristol-Myers Squibb. Antibiotic Levaquin, Cipro, and Bactrim, chemotherapy drugs Carboplatin and Cisplatin, ACE inhibitor Zestril, anti-cholesterol drug Zocor, and antidepressant Cymbalta complete the remaining places on the list of 10 drugs most frequently reported for their safety issues, target of consumer groups, and subject to litigations.

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Cialis Side Effects Lawsuit

 

Viagra Side Effects Lawsuit

Popular erectile dysfunction drugs, Viagra and Cialis, can cause serious health problems. A recent survey by a renowned health website has revealed that the doctors, who were interviewed by the website, preferred prescribing Viagra to Cialis for erectile dysfunction problem because of fewer side effects. It even found many doctors asking patients not to use Cialis as the drug can cause deadly health problems, such as flu-like symptoms, hazed vision, severe lower back pain, and headache. The website notes that the continuous research has led to efforts in limiting major side effects of Viagra.

The FDA approved Viagra on 27 March 1998 and Cialis on 21 November 2003 for erectile dysfunction treatment. While Pfizer produces Viagra, Cialis is manufactured by GlaxoSmithKline. Both drugs became instantly popular, and today, more than 60 million people in the United States use these drugs. However, both reported incidents and clinical trials have shown that these drugs can cause several side effects, ranging from body pain and fever to heart stroke and permanent hearing loss.

Erectile Dysfunction Drugs Linked to Sudden Loss of Hearing

The FDA issued a warning in October 2007 linking Cialis, Levitra, and Viagra with deafness and called for revised labels on these ED drugs. This was prompted by 29 reports of sudden hearing loss caused by these drugs. The first of these reports was published in the Journal of Laryngology & Otology, April 2007 issue, stating how a 44-year-old man in India suddenly lost his hearing function after using Viagra for 15 days. It was followed by more reports and clinical trials that led the federal regulator to believe that there was a strong temporal relationship between ED drugs and sudden hearing loss in patients.

British Study: ED Drugs Cause NAION or Eye Stroke

The British Journal of Ophthalmology reported in 2006 that using Viagra put people with high blood pressure or heart attack at higher risk of non-arteritic anterior ischemic optic neuropathy (NAION), commonly called stroke of the eye. A study by Birmingham’s University of Alabama confirmed NAION in patients within three days of using Viagra.

Research by the Public Citizen Health Research Group, a consumer advocacy group, claims that men using ED drugs are at a greater risk of developing NAION. While those taking Viagra are 18 times more prone to it, using Cialis makes them 25 times more vulnerable.

FDA: ED Drugs Cause Vision Loss

The FDA received 43 reports of vision loss caused by use of ED drugs between 1998 and 2004. The victims were found to be using Viagra in 38 cases, while the rest used Cialis and Levitra. The manufacturers of the three ED drugs were asked to issue warnings to this effect.

Side Effects Proved in Clinical Trials

Various reports and clinical trials found the following side effects of Cialis and Viagra, the two most popular ED drugs.

Cialis Side Effects

GlaxoSmithKline's Cialis is commonly known as the weekend pill. It has PDE5 inhibitor tadafil, which maintains longer duration of erection during sexual stimulation. The list of its side effects is equally long. Most men using Cialis experience headache, muscle aches, indigestion, back pain, and stuffy or running nose. These side effects appear as result of tadafil’s vasodilate quality that widens blood vessels. Back ache and muscle pain persist even 24 to 48 hours after consumption of the drug.

Many using this drug complain of dizziness, heartburn, and stomach upset. Sometimes severe allergic reactions caused by the drug can be fatal. Fainting, painful erection, seizures, and vision changes are also associated with men using Cialis. The clinical studies have shown that the drug can lead to the following major health problems.

Cialis causes hypersensitivity reactions in human body, such as urticaria, dermatitis, Stevens-Johnson syndrome, asthenia, and pain.

Cardiovascular problems caused by the drug can be more serious. Angina pectoris, hypotension, chest pain, sudden cardiac arrest, myocardial infarction, and stroke are associated with tadafil use. Many of these problems occur with or without sexual activity.

Digestive health issue associated with Cialis are abnormal liver function, GGTP increased, dry mouth, loose stools, upper abdominal pain, and vomiting.

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Abilify Side Effects Lawsuit


Abilify is a medication that is used for schizophrenia, bi-polar disorder and other like mental illneses.

It is used for major depressive disorders in adults as an add-on-treatment to antidepressants. It is also used for  pediatric patients, ages 10 to 17, as a treatment of mixed manic episodes associated with Bipolar 1 Disorder and for treatment of Schizophrenia in adolescents ages 13 to 17.

Psychosis related to dementia in elderly people increases the risk of death, compared to placebo, in those patients treated with antipsychotic medicines including Abilify. Abilify can also increase suicidal thoughts especially within the first few months of treatment or whein the dose is changed in some children, teenagers, and young adults.

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Actonel Side Effects Lawsuit 

Actonel is risedronate sodium tablets used for the treatment of osteoporosis.

Risedronate sodium is a white and odorless fine crystalline powder that is soluble in water and aqueous solutions. It is insoluble essentially in common organic solvents. All dose strengths include the following inactive ingredients:

  • Crospovidone
  • Hydroxypropyl Cellulose
  • Hypromellose
  • Magnesium Stearate
  • Microcrystalline Cellulose
  • Polyethylene Glycol
  • Silicon Dioxide
  • Titanium Dioxide

The dose strength-specific ingredients are as follows:

  • 5mg ferric oxide yellow, lactose monohydrate
  • 30mg lactose monohydrate
  • 35mg ferric oxide red/ ferric oxide yellow lactose monohydrate
  • 75mg ferric oxide red
  • 150mg FD&C blue no. 2 aluminum lake
 
 
 Actonel possesses an affinity for hydroxyapatite crystals in bone and it acts an antiresorptive agent. Actonel inhibits osteoclasts at cellular level that hold normally to the bone surface but show evidence of reduced active resorption.
 
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