Enbrel Side Effects
According to a public health alert issued by the FDA in April 2011, use of popular arthritis drug Enbrel can lead to blood cancer. Enbrel, trade name of Etanercept, is a TNF inhibitor co-marketed by Pfizer and Amgen in North America. Available in both powder and premixed liquid form, it was one of the most sold drugs in the U.S. market in 2010 with sales exceeding $3 billion. Enbrel is known to treat autoimmune disorders, such as plaque psoriasis, rheumatoid and psoriatic arthritis, excessive inflammation, and ankylosing spondylitis, in adults and prevent damages to joints caused by these diseases. It helps in the treatment of juvenile rheumatoid and polyarticular idiopathic arthritis in children above 2 years of age.
The immune system mistakenly attacks and destroys its own cells in people suffering from autoimmune problems. Enbrel prevents this by reducing the production of a certain protein that helps the immune system fight invaders. However, such action by the drug leads to serious and fatal side effects. The decrease in the number of white blood cells caused by the drug puts patients at a great risk of fatal infections. Teenagers and young adults with ulcerative colitis are likely to develop a rare, fatal cancer, which affects the liver, lymph, bone marrow, and spleen. Enbrel has also been linked to night sweats, loss of appetite, breathing problems, rapid heart rate, jaundice, and
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