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Lipitor Lawsuit Lipitor Side Effects

1 year 8 months ago #16 by Humanity
various health concerns in users. While headache, dizziness,...

Crestor Lawsuit Lipitor Side Effects


Setting a historic milestone in the U.S. pharmaceutical industry, a Washington federal judge has granted Ranbaxy exclusive rights to market generic Lipitor for six months. On May 2, the court dismissed Mylan's suit challenging the FDA decision to allow Ranbaxy exclusive rights to sell generic version of the drug. Ranbaxy has plans to introduce the drug with generic atorvastatin calcium in the United States on November 30. The new version will give users an option to buy Lipitor at a cheaper rate.

Sold by Pfizer, lipid-lowering medicine Lipitor is the top-selling prescription drug in the world. Lipitor lowers blood cholesterol, stabilizes plaque, and forbids strokes through anti-inflammatory mechanisms. It inhibits HMG-CoA reductase enzyme that helps in the production of cholesterol in humans. However, the drug can cause several side effects, including devastating effects on human muscle and nerve cells. Memory loss, fatigue, myopathy, insomnia, chest pain, urinary tract infection, myalgia, and severe allergic reaction are among the serious side effects of Lipitor.

A feature story entitled "Life After Lipitor" published by Californian newspaperTahoe World on January 27, 2004 highlighted the plight of a Lipitor user from Tahoe City. Doug Peterson, the victim, developed severe neuromuscular problems within two years of taking Lipitor. He experienced lack of muscular coordination, loss of effective motor skills, balancing problems, and trouble talking. His health began improving after he stopped taking the drug. It followed by several reports in medical journals and websites highlighting numerous adverse side effects of the drug. Since then it has been linked to multiple sclerosis, memory loss, motor neuropathy, vertigo, disorientation, and stiffness in neck and calf muscles as corroborated by the users of the drug.

Lipitor Side Efects Class Action Lawsuit Attorney

A class action lawsuit was filed against Pfizer in June 2006 in New York State Supreme Court alleging failure to inform doctors and patients about serious side effects linked to Lipitor. It claimed that the drug caused memory loss and debilitating muscle and nerve problems to several users in New York and Atlanta. One of the plaintiffs, 60-year-old Atlanta man Charles M. Wilson, had complained that he continued suffering balancing problems, memory loss, and fatigue even three years after giving up Lipitor. Another lawsuit by 47-year-old New Yorker Michael Mazzariello alleged that he incurred debilitating damage to muscle cells and loss of memory after using cholesterol-lowering drugs, such as Lipitor. The complainants were of the view that Pfizer promoted the drug as safe and with minimal risks in its ads while doctors and patients came to know about its more dangerous side effects after using it.

Lipitor Side EffectsDangerous Lipitor

Atorvastatin, the main component in Lipitor, causes
various health concerns in users. While headache, dizziness, constipation, back pain, infection, and flu-like syndrome are common side effects of the drug, clinical studies show that it can have more serious health problems.

Lipitor Side EffectsGastrointestinal Risks

Gastrointestinal problems are the most common side effects of anti-cholesterol drugs, such as Lipitor. These risks include dyspepsia, abdominal pain, diarrhea, and flatulence. Decrease in HMG-CoA reductase also causes pancreatitis, loss of appetite, and vomiting.

Lipitor Side Effects Hepatic Problems

Aatorvastatin causes changes in liver functions by inhibiting HMG-CoA reductase. Several users of the drug contacted hepatitis, cirrhosis, cholestatic jaundice, hepatic necrosis, and liver failure after taking it over a long period of time.

Lipitor Side EffectsMusculoskeletal Problems

Most of the Lipitor side effect complaints are related to musculoskeletal problems. There are hundreds of reports of myopathy, disintegration of skeletal muscle tissue, myoglobinuria, and renal failure caused by the drug. Statins, the class of anti-cholesterol drugs, are associated with risk of advanced age, hepatic dysfunction, diabetes mellitus, early onset of nephrotic syndrome, myalgia, and tendon rupture in patients.

Lipitor Side EffectsHematologic Disorders

Lipitor is linked to hematologic side effects, such as hemolytic anemia, and leukopenia. These occur as a result of HMG-CoA reductase inhibitors present in the drug.

Lipitor Side EffectsEndocrine Disorders

Aatorvastatin leads to hypospermia, hormonal imbalance leading to breasts in male, and thyroid dysfunction. Acid maltase deficiency, a genetic disorder commonly known as  Pompe's Disease is also found to be caused by the drug.

Lipitor Side EffectsGenitourinary Problems

A 77-year-old female Lipitor user with a history of hypercholesterolemia is reported to have suffered from hemorrhagic cystitis coincident after using the drug for week. Her problem considerably decreased after she stopped taking the drug.  According to reports, several statin users reportedly experienced erectile dysfunction and testicular pain, but returned to normalcy once they stopped the drug.

Lipitor Side Effects Cardiovascular Risks

Though the drug is claimed to have reduced risk of second stroke in patients, it is linked to various cardiovascular side effects. Users of the drug are prone to chest pain, angioneurotic edema, incidence of hemorrhagic stroke.

Other Serious Lipitor Side Effects
  • Lipitor users are experience respiratory problems, such as bronchitis, pharyngitis, and sinusitis.
  • Ocular problems, including paralysis of the motor nerves in the eye, horizontal diplopia, and blurry vision, are reportedly found in patients during studies on side effects.
  • Users also have psychiatric problems, such as decrease in libido, anxiety, and depression.

Problems With Other Statin Drugs

Lipitor is not the only statin-class drug to have wide-ranging side effects. All anti-cholesterol drugs, such Zocor, Altocor, Lescol, Crestor,Pravachol, Mevacor, impact normal functioning of the liver. The FDA has put these drugs in pregnancy Category X. Advised medical practitioners to take caution while prescribing the drug to patients with diabetes, muscular disorder, kidney problem, and liver abnormalities. Baycol, a statin drug with cerivastatin as the main component, was banned in 2001 after more than 100 deaths caused by it were reported. Its manufacturer Bayer paid $750 million to settle lawsuits. The FDA changed label warnings on another statin drug Crestor after several consumer groups have petitioned for its withdrawal and reports in the Journal of the American Heart Association cited serious side effects on muscles and kidney.


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