Paxil Side Effects Lawsuit
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Paxil Side Effects Lawsuit
Paxil, a paoxentine hydrochloride tablet, is an antidepressant; antidepressants may increase the risk of suicidal thinking and behavior in children and young adults. The drugs also inhabit the risk of overdose and dependency axil is used to treat Major Depressive Disorder, Obsessive Compulsive Disorder, Panic disorder, Social Anxiety disorder, Generalized Anxiety Disorder and posttraumatic Stress Disorder.
For Major Depressive Disorder, Paxil should be administered with or without food as a single daily dose. The initial recommended dose is 20mg/day. Patients who are Non-responsive to 20mg dosage may benefit from 10mg /day up to 50mg/day maximum and changes in dose should take place at the intervals at least one week.
For Obsessive Compulsive Disorder, Paxil should be administered with or without food as a single daily dose. The initial recommended dose is 40mg a day. Patients who are Non-responsive to 20mg dosage may benefit from 10mg /day up to 50mg/day maximum and changes in dose should take place at the intervals at least one week.
For Panic Disorder,Paxil should be administered with or without food as a single daily dose. The initial recommended dose is 10mg/day. The target dose is 40mg/day. Doses may be raised by increments of 10mg/day
For Social Anxiety Disorder, Paxil should be administered with or without food as a single daily dose. The initial recommended dose is 20mg/day. No information on addition benefits for doses higher than 20mg/day is available.
For Generalized Anxiety Disorder, Paxil should be administered with or without food as a single daily dose. The initial recommended dose is 20mg/day and there is no sufficient evidence to prove higher dosage effective.
For Posttraumatic Stress Disorder, Paxil should be administered with or without food as a single daily dose. The initial recommended dose is 20mg/day. There is also no evidence of an effective dose increase for this disorder but, if indicated, dose change should occur in 10mg/day increments.
The selective serotonin reuptake inhibitor, Paxil, is now under the spotlight for suspicions that it may be linked low sperm count in men and also for withholding information on the risk of birth defects when used by women. Documents show that, until it was compelled to do so by the FDA in 2005, Glaxo neglected to publicize warnings about Paxil’s risk. Paxil was approved in 1992 and, with sales of just under $1 billion in 2008, is now one of the most commonly prescribed drugs in the United States.
It is a well known that anti-depressants may affect sexual functions in males and females and can also negatively impact erectile function and ejaculation. Studies now show that men who take Paxil can experience sperm damage and impaired fertility. Nearly half of the men taking Paxil and Seroxat, another parozentine, tested with greater levels of “sperm fragmentation” according to New York research. The study also demonstrates that the anti-depressant drugs can cause genetic damage to sperm. 35 health men who took paroxetine were looked at for five weeks in the study. When tested at the beginning of the study fewer than 10 percent of the men showed abnormal DNA fragmentation but when the trial ended and the men were tested again nearly half of them tested positive for signs of abnormal DNA fragmentation. Abnormal DNA fragmentation occurs when the sperm DNA is missing pieces of the genetic code. After the medication was discontinued the sperm return to normal. Dr. Cigdem Tanrikut’s theory is that paroxetine slows the sperms travel though the male reproductive tract causing it to age and become damaged.
The anti-depressants also have negative affects on women and children as it seems that women who take Paxil and such drugs are more prone to having children born with birth defects. GlaxoSmithKline Plc is now facing some 600 cases for allegations that its major antidepressant, Paxil, can lead to birth defects when women who are pregnant take it. An attorney in a recent trial clamed that Glaxo disregarded information that Paxil caused birth defects and advised its scientist not to reveal the potential risk presented to pregnant women by the drug. The lawyer also noted that when rats received Paxil in the initial testing, their pups didn’t last more than four days and that Glaxo’s documents prove that it was aware as far back as 1980 that Paxil could increase birth defect. By 1997 Glaxo established 50 reports of miscarriges or intrauterine deaths. An alert was sent to physicians about the risk by the FDA in late 2005 and Glaxo was asked to update the medication information and warning label on the birth defects.
The following side effects are associated with Paxil:
- Nausea
- Drowsiness
- Dizziness
- trouble sleeping
- loss of appetite
- Weakness
- Tiredness
- dry mouth
- Sweating
- Yawning
- thoughts of suicide
- shakiness
- Restlessness
- Loss of sexual interest
- changes in sexual ability
- blurred vision
- numbness
- tarry stools
- vomit that looks like coffee grounds
- easy bruising, bleeding, fainting,
- fast irregular heartbeat
- muscle weakness
- \Seizures
- change in amount of urine
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