Darvon Side Effects Lawsuit
Darvon, propoxyphene hydrochloride capsules, is used to relieve mild to moderate pain. It is a white crystalline, odorless powder wit h a bitter tasted. The drug is soluble freely in water and has a molecular weight of 375.94. Darvon is chemically 2S,3R)-(+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate (ester) hydrochloride.
Darvon capsules are supplied as 65mg, opaque pink capsules with “Darvon” imprinted in edible black ink on the body. They are provided in bottles of 100. Each capsule contains 65 mg (172.9 µmol) propoxyphene hydrochloride as well as other inactive ingredients such as D & C Red No. 33, F D & C Yellow No. 6, gelatin, magnesium stearate, silicone, starch, titanium dioxide.
The recommended dose of Darvon is 65mg, or one capsule, every 4 hours. The recommended maximum dose of the drug is 390mg/day. Patients with hepatic or renal impairment should consider a reduced total daily dose of Daevon.
Poison Control Center should be called to obtain the most up-to-date information about the treatment of overdose if one were to ever occur. If a propoxyphene overdose were to occur, attention should first be focused on establishing a patent airway and restoring ventilation. Ventilation assisted mechanically, with or without oxygen, may be required and if pulmonary edema is present, positive pressure respiration may be desirable. Antagonist nalxone, the narcotic, will reduce the degree of respiratory depression. 0.4mg to 2mg should be administered, preferably intravenously, promptly.

